AI Engineer & ML Researcher

Johnathan Jia

I build and study machine-learning systems—from model development and rigorous evaluation to scientific computing and production engineering.

Computational scientist with deep biomedical experience, working across research questions, real-world data, and the systems around a model.

150M+clinical events processed
16Kreasoning rollouts analyzed
~99%scientific runtime reduction

Models + evaluation + systems

Selected work

Models and systems built around difficult data.

Work across transformer development, retrieval and ranking, interpretability, and scientific performance engineering.

Clinical sequence modeling2024–Present

TEDDY

A transformer trained from scratch to forecast first-occurrence diagnoses from longitudinal clinical event histories.

150M+raw clinical events tokenized
  • PyTorch
  • Transformers
  • CUDA
  • Clinical sequences
Independent ML research2026

Detectability of Doomed Reasoning Chains

Testing whether residual-stream representations can identify reasoning trajectories that are unlikely to recover before generation completes.

16Kverifier-graded rollouts
  • PyTorch
  • DeepSeek-R1-Distill-Qwen-1.5B
  • MATH
  • Linear probes
Retrieval & ranking2023–Present

MentorMatcher

A production-oriented mentor search system where evaluation led from an unstable LLM judge to a fine-tuned cross-encoder reranker.

  • FastAPI
  • RoBERTa
  • PostgreSQL
  • FAISS
Open-source performance engineering2024

decontX Optimization

Profiling and redesigning a scientific Python bottleneck reduced a large single-cell workload from more than 12 hours to minutes.

~99%runtime reduction
  • Python
  • Sparse matrices
  • Concurrency
  • Single-cell RNA-seq

Current research

Independent · Ongoing · 2026

Can a model know when its reasoning will fail?

I am testing whether residual-stream representations can predict a rollout’s eventual correctness before generation finishes—and where apparent trajectory signal is actually problem-difficulty signal.

Observed pooled AUC0.708with unresolved confounding and calibration questions
Read the research note

Working across layers

Close to the problem, the data, the model, and the system.

My path through biology, quantitative science, computational genomics, and AI engineering shapes how I work: understand the scientific or operational constraint, build the model, measure its behavior, and make the surrounding system reliable.